Download ebook The Clinibook : Clinical Gene Transfer State of the Art
Download ebook The Clinibook : Clinical Gene Transfer State of the Art
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Author: Odile Cohen-Haguenauer
Number of Pages: 586 pages
Published Date: 31 Oct 2012
Publisher: Edp Sciences
Publication Country: United States
Language: English
Type: Pdf
ISBN: 9782842541712
Download Link: The Clinibook Clinical Gene Transfer State of the Art
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This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. Dr Odile Cohen-Haguenauer is the Coordinator of Clingene-NoE, the European Network for the Advancement of Clinical Gene Transfer and Therapy.
Read online The Clinibook : Clinical Gene Transfer State of the Art Buy and read online The Clinibook : Clinical Gene Transfer State of the Art Download and read The Clinibook : Clinical Gene Transfer State of the Art for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook The Clinibook : Clinical Gene Transfer State of the Art ebook, pdf, djvu, epub, mobi, fb2, zip, rar, torrent
The Clinibook : Clinical Gene Transfer State of the Art. Odile Cohen-Haguenauer
Author: Odile Cohen-Haguenauer
Number of Pages: 586 pages
Published Date: 31 Oct 2012
Publisher: Edp Sciences
Publication Country: United States
Language: English
Type: Pdf
ISBN: 9782842541712
Download Link: The Clinibook Clinical Gene Transfer State of the Art
---------------------------------------------------------------
This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. Dr Odile Cohen-Haguenauer is the Coordinator of Clingene-NoE, the European Network for the Advancement of Clinical Gene Transfer and Therapy.
Read online The Clinibook : Clinical Gene Transfer State of the Art Buy and read online The Clinibook : Clinical Gene Transfer State of the Art Download and read The Clinibook : Clinical Gene Transfer State of the Art for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook The Clinibook : Clinical Gene Transfer State of the Art ebook, pdf, djvu, epub, mobi, fb2, zip, rar, torrent